Definitions and general characteristics
In a hydrogen bond, the electronegative atom not covalently attached to the hydrogen is named the proton acceptor, whereas the one covalently bound to the hydrogen is named … See more

Water
An ubiquitous example of a hydrogen bond is found between water molecules. In a discrete water molecule, there are two hydrogen atoms and … See more

A symmetric hydrogen bond is a special type of hydrogen bond in which the proton is spaced exactly halfway between two identical atoms. … See more

The Hydrogen bond is relevant to drug design. According to Lipinski's rule of five the majority of orally active drugs have no more than five … See more

The concept of hydrogen bonding once was challenging. Linus Pauling credits T. S. Moore and T. F. Winmill with the first mention of the hydrogen bond, in 1912. Moore and Winmill … See more

Hydrogen bonding plays an important role in determining the three-dimensional structures and the properties adopted by many proteins. Compared to the C−C, C−O, and C−N bonds that comprise most polymers, hydrogen bonds are far weaker, perhaps 5%. Thus, … See more

The hydrogen bond can be compared with the closely related dihydrogen bond, which is also an intermolecular bonding interaction involving … See more